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Weekend Editor

@weekend_editor@mathstodon.xyz
mastodon 4.7.2
  • Open on mathstodon.xyz

Retired physicist, after a career in machine learning & stats mostly for cancer drug discovery. Now blogging about stats in the news.

Avatar: convergence basins in the complex plane of Newton's algorithm searching for the cube roots of unity. (After a NYT column by @stevenstrogatz@mathstodon.xyz, long ago.)

Header: Quote from GK Chesterton, London Daily News, 1905-Aug-16 on epistemic humility and the ability to say "I am wrong" as the foundation of idealism.

#statistics #physics #r

315 Followers
113 Following
50 Posts
Joined November 21, 2022
Blog:
https://www.someweekendreading.blog/
BlueSky:
@weekend-editor.bsky.social
Email:
SomeWeekendReadingEditor@gmail.com
Member:
Locally Flat Earth Society
Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 2mo ago

RE: @paulfoerster@swiss.social

Voting Republican is evil.
Not voting is being complicit with evil.
Voting 3rd party is being complicit with evil AND bad at math.

swiss.social

Paul Förster :verified_blue:: "#Today on #Bluesky. https://bsky.app/profile/don…" - swiss.social

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@paul_ipv6 I also do not want to see your discord, I will not look at your facebook page, I will not install whatsapp, and I will never, ever, under any circumstances, talk to your chatbot. I want to *read* a manual. I want you to *commit* to what's in that manual.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago

RE: @AkaSci@fosstodon.org

I see the innumeracy of the rulers has not gotten any better in the last couple of years.

https://www.someweekendreading.blog/math-illiterate-rulers/

fosstodon.org
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@jackdaniel@functional.cafe Yes, this is fast. But most people won't see it, because they are in the grip of the myth that "Lisp is slow". You get the most mileage by comparing against things people think are fast, at least for certain tasks, like C or Fortran. For a venerable example of the art of making that comparison, Steele had a number of biting comparisons between MacLISP and Fortran back in the day. Here are a couple that had quite an impact on changing my views, back in ancient times: GL Steele, "Fast Arithmetic in MacLISP", MIT AI Memo 421, Sept 1977. https://dspace.mit.edu/entities/publication/81ec8fec-0598-49e9-9973-0abaf85fa6d7 GL Steele, "Debunking the expensive procedure call myth", MIT AI Memo 443, Oct 1977. https://dspace.mit.edu/entities/publication/77b3eea1-50be-4e3f-b578-264484ee0f1a
dspace.mit.edu

Fast Arithmetic in MACLISP

MacLISP provides a compiler which produces numerical code competitive in speed with some FORTRAN implementations and yet compatible with the rest of the MacLISP system. All numerical programs can be run under MacLISP interpreter. Additional declarations to the compiler specify type information which allows the generation of optimized numerical code which generally does not require the garbage collection of temporary numerical results. Array accesses are almost as fast as in FORTRAN, a

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@jackdaniel@functional.cafe Gotta respect the classics! That book is interesting in that it not only explores how to create whole new object systems with the metaobject protocol, but also explains how to *implement* things like CLOS nicely. (Also, I'm fairly sure I was Gregor's physics TA back in the late 1970s or so. :-) (Also also, respect for Borges in the background in that shot. Magical realism sometimes creeps into our software thinking. :-)
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@johncarlosbaez@mathstodon.xyz @highergeometer@mathstodon.xyz @eighteyes@hachyderm.io ... or, if you're writing in your own notebook about your own research: "How much detail is my later self going to want to know? It's all fresh in my mind now, but in a couple of years it will not be." I tend to over-document stuff because that fool who I'm going to become in a couple of years will have forgotten everything important, and will remember only trivialities. I have very regrettable empirical data to confirm this. :-(
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@johncarlosbaez When I was starting out doing statistics in oncology bioinfromatics, I had some gene expression data for cancer cells from which I was supposed to find gene patterns that indicated the onset of cell death (apoptosis). Some of the genes that came up were the SNAP and SNARE families. Back in those days, they were annotated as neuro genes, making membrane vesicles for neurotransmitters and such. The first response of my biologist client was a rather rude one: "Get that neuro crap out of my data!" Well. It turns out they're also involved in "membrane blebbing", in which cell surface membranes make vesicles to eject cytoplasm, as a part of both cell division AND cell death by apoptosis. So "that neuro crap" was a set of genes involved in reshaping membranes, the result of which depends on if the cell is squirting neurotransmitters, dividing, or dying. Dying was the relevant context in that dataset. Context matters! I was polite, but it was with great satisfaction that I could eventually point this out to the rude biologist. :-) https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/blebbing
sciencedirect.com
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 3mo ago
Replying to
@FluentInFinance@mastodon.social The ones who made the most money in the American gold rush of the 1850s were the ones selling wheelbarrows, picks and shovels. But... gold rushes come to an end when people finally do the math. Meta may make some money selling wheelbarrows... but the AI bubble will pop nonetheless.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@FluentInFinance@mastodon.social Not too long ago, we'd have said cheaper electricity enabled more profitable crypto mining. Crypto was a grift; pretty sure AI is not an improvement.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 2mo ago

Today's blog post:

A seasonal song for this moment in American politics.

99 days to the primary,
99 days remain.
Mark 1 down, canvass your town,
98 days to the primary!

My cats also have opinions on this subject. They are correct.

https://www.someweekendreading.blog/99-days-to-primary/

someweekendreading.blog

A Seasonal Song for American Politics

A new seasonal song, for this moment in American politics!

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@grimalkina And now, alas, Trump has fired the entire governing board of the NSF: https://www.science.org/content/article/trump-fires-nsf-s-oversight-board
science.org
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@ColinTheMathmo @vpunt Oh, I have *so* many battle scars from this! Imagine my frustration when Excel took gene expression data and converted gene names like DEC10 to dates, then munged the dates DIFFERENTLY, depending on whether the data was last saved by American or European colleagues! (True story, actually seen in the wild.) Some genes have actually been renamed because this error in Excel is so damn persistent. In 2021, about 30% of papers contain mangled gene names in supplementary data: https://www.nature.com/articles/d41586-021-02211-4 Same in 2016, multiple sources: https://link.springer.com/article/10.1186/s13059-016-1044-7 https://www.science.org/content/article/one-five-genetics-papers-contains-errors-thanks-microsoft-excel This has been going on for decades, since AT LEAST 2004, which is when it bit me: https://link.springer.com/article/10.1186/1471-2105-5-80 You can't get Microsoft to fix it, since it's not a "business problem". You can't get biologists to stop using Excel, becaues it's a "bioinformatics problem". Ultimately, you CAN get the international standards body that assigns HUGO symbols to human genes to CHANGE 27 GENE NAMES to bulletproof them against Excel mishegoss: https://www.theverge.com/2020/8/6/21355674/human-genes-rename-microsoft-excel-misreading-dates At that point, Microsoft was sufficiently embarrassed to put in a switch in Excel to turn off data conversion (apparently all of it, not just genes & dates). I was retired at that point, but I will bet (small amounts of) actual money that ALMOST NO BIOLOGIST KNOWS HOW TO TURN THAT SWITCH OFF, so the problem would have persisted had the genes not been renamed.
nature.com
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@skeletor@mas.to The word "repent" comes from the Latin "repaenetere", which literally means "to rethink", decide what went wrong, and do better next time. The Greek equivalent "metanoia", literally something like "thinking about thinking", usually translated as "changing one's mind", also implies trying again. The Hebrew root behind all of those, "teshuvah", means to "return" to your roots as an intrinsically good person, and try again. Or, as the playwright Samuel Beckett put it: "Try again. Fail better next time." It's a process of continuous improvement, not sudden success.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 3mo ago
Replying to
@geonz@mathstodon.xyz @workchronicles@mastodon.social Yeah, I spent an entire career saying "I must be so stupid" in the last panel. No success can compensate, apparently.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 3mo ago
Replying to
@johncarlosbaez@mathstodon.xyz Needs Roger Bacon's famous magical brass head. Any prankster-sculptors available? Pretty sure Banksy would do it. https://en.wikipedia.org/wiki/Brazen_head
en.wikipedia.org
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@paul_ipv6 The experience FOR THEM is better in the app, because they can data harvest like mad. In a browser, I can control their use of javascript, block ads, and have little snitch strangle their outbound network traffic. Though, if they make me do that even in a web browser, chances are I want nothing to do with them in the future. I wish we could all proclaim that, as loud as possible, so the vendors would maybe get it.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 3mo ago
Replying to
counting calories, kinda
@jenniferplusplus@hachyderm.io Now I've got _Wallace and Gromit_ memories playing in my head. "Not even Wensleydale?!"
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@anarodrigues@front-end.social Also, it's pretty sure that in the past layoffs targeted women (a) statistically significantly more often and (b) with bigger strength of effect (i.e., laid off a larger % of women). https://www.someweekendreading.blog/2022-tech-layoffs-bias/
someweekendreading.blog

2022 Tech Layoffs: Gender Bias?

Somebody asked me – ok, really I saw it on Mastodon, but close enough – about gender bias in the tech layoff cycle of 2022. Is it really true that women were targeted?

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@AmenZwa You need to meet the screenwriter John Rogers @johnrogers.bsky.social who is also a fountain pen nerd. I think he's more active on BlueSky, though.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@rogersm@mastodon.social @jackdaniel@functional.cafe The paperback seems to be in stock at Amazon? https://www.amazon.com/Art-Metaobject-Protocol-Gregor-Kiczales/dp/0262610744
amazon.com
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@AlZheimer There's music appreciation, and then there's *true* music appreciation.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@johncarlosbaez@mathstodon.xyz From a couple years ago, on the unaffordability for the rest of us of keeping the rich around. GINI coefficients, class mobility vs wealth inequality, and so on. https://www.someweekendreading.blog/unaffordable-rich/
someweekendreading.blog
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@skeletor@mas.to While Mother Theresa was far from perfect, she's famous for (probably) saying: “It’s not necessary to be a saint to do good. You need willing hands, not clean ones.” — Mother Theresa (From my quotes page: https://www.someweekendreading.blog/quotes/#:~:text=%E2%80%9CIt%E2%80%99s%20not%20necessary%20to%20be%20a%20saint%20to%20do%20good%2E%20You%20need%20willing%20hands%2C%20not%20clean%20ones%2E%E2%80%9D%20%E2%80%94%20Mother%20Theresa )
someweekendreading.blog

Quotes I

Occasional tart thoughts of a grumpy old retired scientist, your humble Weekend Editor.

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@camertron@ruby.social @joeldrapper@ruby.social "History will judge us either stupid or complicit, and we know we are not stupid." -- Jack Hardy, "Ask Questions" https://www.youtube.com/watch?v=zX7sARa5Bcc

Jack Hardy - Ask Questions

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@danwwilson@rstats.me It gets worse. Excel infamously will convert certain gene names (under the HUGO standard) to dates, like DEC10. For decades, you could not turn it off; I hear rumors that now there is a switch somewhere to turn it off, but nobody remembers where it is. So: I once had a dataset that biologists kept loading into Excel, despite my warnings. It came out DIFFERENTLY in the US and Germany. After much frustration, it turned out to be a gene name being converted to a different date format in each country! You will debug MANY, MANY things before you check that.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@nigelpstanley@mastodonapp.uk This is... absolutely gorgeous. 4 ways with stained glass + 4 ways that lead... elsewhere. I want to apply to the caretakers for permission to lie on the floor for an hour, and weep, with... well, probably joy, and sadness.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@AmenZwa Knew all of these but MCAS. Did you mean the Massachusetts Comprehensive Assessment System (high school graduation test), or Mast Cell Activation Syndrome, or... ?
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@AmenZwa Oooh! The 737Max software thing. I totally didn't see that one. MCAS hereabouts almost always refers to the high school test, unless you're medical in which case it's the other. I guess I don't hang around with aero/astro folk enough.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@spaf Pretty sure I met him in the 70s, or at least the people in his circle.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@siderea Instead of a RAID, I'm getting (next week?) a Synology NAS with 2 bays, 4Tb drives in each bay. The backups will alternate drives for replication. At least, that's what my Mac systems guy recommended, and he's been pretty good in the past.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@kentpitman@climatejustice.social @screwlisp@gamerplus.org @larsbrinkhoff@mastodon.sdf.org @eswenson@c.im I remember being at a talk you gave on your semi-automated Symbolics MACSYMA conversion. I asked you what it did about comments, since it processed S-expressions from which comments were removed. You shrugged and said, "Fortunately..." and then everybody laughed because we all knew there were so few comments that they could be handled one-by-one. :-)
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@mnl What does the switch do, in this configuration?
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@ergative@wandering.shop Always? I mean, that's partly what it's *for*?
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@abstractcode The traditional version of this argument involves tumbrels and guillotines.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@amszmidt@mastodon.social @mnl@hachyderm.io Helluva fuse somewhere, in that case.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@vpunt @ColinTheMathmo Yes, a correction worthy to note.
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Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@tlapka Well... later, I *will* be older, more or less by definition.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@Garwboy NotebookLM made a 'podcast' about my blog. Two happy-talk 'hosts' ask each other questions, get most details wrong, and fail to answer the questions. A friend described it as "the verbal equivalent of Muzak", which apparently means AI is unavoidable but best ignored. I wrote about it here: https://www.someweekendreading.blog/someweekendreading-ai-podcast/
someweekendreading.blog

An AI-Generated Podcast About This CLBTNR?!

Google has done a very silly thing: feed them some information, and they’ll make a podcast with 2 AI hosts ‘discussing’ it. We fed them this Crummy Little Blog That Nobody Reads (CLBTNR). The results are… amusing?

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@Catvalente@wandering.shop I'm impressed -- with all 4 of you.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@ftp_alun @ColinTheMathmo @vpunt It's because Excel is trying to be "helpful" by intervening to CHANGE YOUR DATA WITHOUT YOUR CONSENT OR KNOWLEDGE, and there was for approximately 20 years NO WAY TO TURN IT OFF. The result is nonsensical gene names in approximately 30% of all papers about genes, because you CANNOT pry Excel out of people's hands even after they see the damage it does. I think a data analysis tool should respect data WAY more than that! Excel fits the term "data analysis tool" loosely at best, but it's the tool to hand and what people will use if they don't know better. Ask @louisepryor sometime about her days as an actuary, patiently explaining to bankers why they can't write massively complex spreadsheets and expect anything other than disaster. Financial analysis is exactly the intended application of spreadsheets, after all. (Oh, and source control too. Much of the world's financial system apparently used to run without source control. *Exactly* which version was running? Nobody was quite sure...)
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@nosrednayduj Last year I ordered something which initially got as close as Boston. But instead of being shipped from there to my home in deepest, darkest suburbia... It got sent to Puerto Rico. Apparently the folks there were as confused as me, since they bounced it around among various post offices in PR for a week. Finally somebody clued in on the ZIP code, and sent it along its proper way. I have literally no idea how that happened.
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 2mo ago
RE: https://mastodon.social/@arstechnica/117049561381886953 "Claiming authority over limit set by Congress": basically, rule of law matters so little to Republicans that Trump can do whatever and dare the rest of us to stop him if we can.
mastodon.social
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@christianp My permission to operate came in a couple weeks after the install, but the state approval so I could get reimbursed for solar energy credits took about 6 months. Of course, all the energy I generated in that time does not count, since it was pre-approval. There are *enormous* numbers of blockades in the way of getting a working solar installation!
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Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago

Jack Hardy, "May Day".

https://www.youtube.com/watch?v=UylFlOlveV0

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@ColinTheMathmo Earliest cite I could find was Tal Waterhouse on Twitter, 2018-May-03. (Caution: link to X/Twitter, probably best avoided until you really need it.) https://x.com/iiTalW/status/991905585174986753
Tal Waterhouse (@iiTalW) on X
X (formerly Twitter)

Tal Waterhouse (@iiTalW) on X

People who can't distinguish between etymology and entomology bug me in ways I cannot put into words.

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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@ColinTheMathmo @tao @dimpase There have been some really interesting psychological studies on people who use LLMs heavily (the Big Five personality test and so on). Whether they self-select or whether the LLM *makes* them that way is still open. Here's a walk-through of one of those studies: https://www.someweekendreading.blog/who-uses-ai/
someweekendreading.blog
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Open post
Weekend Editor @weekend_editor@mathstodon.xyz
· 5mo ago
Replying to
@christianp The OEIS says, "if two such numbers exist, the smaller is chosen." It looks like they aren't following that rule, and hence the sequence is occasionally double-valued.
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Weekend Editor @weekend_editor@mathstodon.xyz
· 6mo ago
Replying to
@ColinTheMathmo "... and, in some parts of the world, it might also be February 1st."
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Weekend Editor @weekend_editor@mathstodon.xyz
· 2mo ago
Replying to
@MissConstrue@mefi.social Jumanji, but for the rule of law.
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Weekend Editor @weekend_editor@mathstodon.xyz
· 4mo ago
Replying to
@Catvalente@wandering.shop Lotta oomph from just a few words. Impact, tightly packed.
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