jcrabapple
Elder Millennial. Husband. Girl dad. Dog owner. IT Professional. Tech enthusiast. CSS tinkerer. Music lover. Huge Sleep Token and Bilmuri fan.
Non-practicing white person.
Grew up in MD. Lived in and around Baltimore for a long time. Currently living in VA with my wife, 3 youngest daughters, and our 2 dogs.
Admin of:
https://DMV.Community (Mastodon)
The environmental cost of running LLMs keeps climbing, but a few inference providers are running on 100% clean energy out of the box:
- Regolo (https://regolo.ai/sustainable-ai/) EU-hosted GPU clusters running on wind and solar power, using zero-water cooling.
- GreenPT (https://greenpt.com/api) European OpenAI-compatible API powered 100% by renewables in ISO-certified datacenters.
- Riveon (https://riveon.io/) Swiss provider with Finnish GPU sites powered 100% by renewables, offering OpenAI-compatible endpoints.
- Upgreat (https://www.upgreat.ai/) Carbon-aware EU compute that schedules workloads around clean energy windows from on-site solar farms.
Good options if you want clean compute for open-weights inference without relying on carbon offsets.
#AI #GreenTech #OpenSource #Sustainability #MachineLearning #Tech
💊 A viral video calls benfotiamine (fat-soluble vitamin B1) a "revolutionary" anti-inflammatory breakthrough. The real story is more complicated.
The video references a real June 2026 study where researchers used computational drug repurposing to identify benfotiamine as a P2Y14R antagonist. P2Y14R is a genuine inflammatory target. The study tested it in mice with colitis and gouty arthritis and reported positive results.
But here's what the video leaves out:
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The study is preclinical (mice + computer models), with 0 citations. "Revolutionary" is a stretch.
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Multiple human RCTs found NO anti-inflammatory effect. A 24-month trial (300mg/day) in Type 1 diabetics showed no change in inflammatory markers. A 12-week trial (900mg/day) in diabetic nephropathy found no effect on inflammation. The BOND study (12 months, 600mg/day) found no effect on neuropathy outcomes.
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The creator, Dr. Rick Pescatore, founded BellyMD, a supplement company selling benfotiamine products. This financial relationship is not disclosed in the video.
Benfotiamine is real, safe, and inexpensive. The preclinical anti-inflammatory science is genuine. But human trials have not confirmed the anti-inflammatory claims, and the "breakthrough" framing serves a product the creator sells.
Read more: https://pmc.ncbi.nlm.nih.gov/articles/PMC3329837/ https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040427 https://doi.org/10.1136/bmjdrc-2025-005773




