T.R. Endless

"What we found, again and again, was that these patients were not treatment resistant in any meaningful psychiatric sense. Their brains were being starved of blood. The sympathetic system was failing to move blood upward, or the parasympathetic system was dilating vessels at exactly the wrong moment, or both. Once you measure the two branches independently and correct the specific imbalance, the so-called depression lifts, not because we treated depression, but because we treated the physiology that was masquerading as depression"

Nearly half of the study cohort (48.3 percent) had been diagnosed with long- or post-COVID syndrome, a population now recognized as a vast and troubled reservoir of autonomic dysfunction.

https://www.news-medical.net/news/20260331/Treating-autonomic-dysfunction-can-relieve-symptoms-of-treatment-resistant-depression.aspx

ACEP-CAPE sent this to the Office of the Auditor General of Canada on April 30, 2026

Submission on behalf of the Canadian Association of Professional Employees’ Disability Justice Caucus

Canada is experiencing a mass disabling event driven in large part by the ongoing transmission of COVID-19 and other communicable diseases. Disability rates are rising according to data from Statistics Canada, and scientific guidance from the Office of the Chief Science Advisor of Canada has documented the long-term impacts of post-COVID conditions on cognitive, cardiovascular, and functional health. COVID-19 remains a leading cause of death in Canada and contributes to the conditions that drive the two leading causes of mortality, including cardiovascular disease. These realities shape the accessibility needs of the workforce and cannot be ignored in any serious assessment of workplace accessibility...

https://www.acep-cape.ca/sites/default/files/2026-04/Letter%20to%20AG_EN.pdf

@pandemicene

#CovidIsNotOver

It may seem intimidating, but let me assure you that you could easily run a fediverse¹ instance for you and a few friends / family members. And although it's gotten a bit more expensive in the past month, getting your hands on a VPS in a Canadian datacentre and a .ca² domain is still very reasonably priced.

If you're interested in such a thing but don't know where to start, I'll gladly act as sherpa, gratis.

--
¹GoToSocial, Mastodon, Glitchsoc, Sharkey, etc

².ca is one of the cheapest, but you can use any top-level domain; eg .com, .cc, .social, etc

Despite effective antiretroviral treatment, HIV remains in the body in a dormant form, known as the viral reservoir. This reservoir is the main reason HIV cannot currently be cured. In the study, researchers at Karolinska Institutet investigated whether the gut microbiota—the bacteria living in the gut—might be linked to the size of this reservoir.

The study included 30 people living with HIV who had been on long-term antiretroviral treatment. The researchers analyzed blood samples to measure levels of intact HIV DNA and combined these data with detailed profiling of the participants' gut microbiota using whole-metagenomic sequencing. The results show that certain bacterial species and metabolic processes in the gut differed between individuals with larger and smaller HIV reservoirs.

"We observed that specific patterns in the gut microbiota were associated with differences in the size of the HIV reservoir. This suggests that interactions between the body and the microbiome may influence how much virus remains in a dormant state"

https://medicalxpress.com/news/2026-04-gut-bacteria-linked-latent-hiv.html

# canada:zeroes.ca -- a group chat room for all things maple-flavoUred, eh

:canada: :matrix: 🗪

#Matrix

Wealth, fame, and power are results of quantity

Ethics, integrity, and sustainability are results of quality