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Rupert Overall

@rupertoverall@fosstodon.org
mastodon 4.7.3
  • Open on fosstodon.org

I research the genetics behind brain ageing. My work includes phenomics (automated high-throughput behavioural phenotyping), systems genetics (multi-omics and quantitative trait locus mapping) as well as molecular pathway modelling (using disease maps, Boolean models and network analysis). All focussed on the question: how does neuron function change with age?

#ageing #aging #genetics #genomics #systemsgenetics #qtl #lifespan #cognitive #healthspan #sbgn #openscience #behavior #behaviour

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0 Following
9 Posts
Joined December 30, 2022
Website:
https://rupertoverall.net
GitHub:
https://rupertoverall.github.io
ORCID:
https://orcid.org/0000-0002-3882-6073
Pinned Project:
https://rupertoverall.net/Rtrack/
Open post
Rupert Overall @rupertoverall@fosstodon.org
· 12mo ago

Rtrack 2.0.4 is on CRAN. If you work in the experimental behaviour field - this is for you. The latest update brings more flexibility for experiment design and data visualisation alongside the usual robustness improvements. If you already use Rtrack - enjoy the improvements! If you are not yet using Rtrack - check out what you have been missing...
https://rupertoverall.net/Rtrack/

#OpenSource #behavior #behaviour #Science #RStats

rupertoverall.net
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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 15mo ago

Is it a universal truth that any button/link/menu item syaing "Help" does not lead to anything helpful?

You'd think that the authors of a software would be the people best placed to know how to solve problems related to their work. It is essentially always the worst place to seek assistance though.

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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 45mo ago
Replying to
@openscience @andrewdessler If these were stocks - would you sell now?
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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 16mo ago
Replying to
...so I guess we should enjoy the golden age while it lasts.
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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 8mo ago

Wonderful to see this study published!
A deep dive into the genetics of polyglucosan bodies in the brain.

Especially rewarding for me as the work began during our research Summer School (https://sysgenschool.org/) in 2022 - amazing to see how this collaboration has flourished and expanded since then!

https://www.sciencedirect.com/science/article/pii/S2405471225003217

sysgenschool.org
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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 12mo ago

Rtrack microtutorial - 1. Plotting

Rtrack has single-command built-in plotting for search paths (a, b), density maps (c, d), variable overviews (e, f) and strategies (more on that to come). Quick, easy and customisable (b, d, f). These plots can all be saved in publication-quality vector format.

English not your language of choice? No worries, just hack the plot with a few simple parameters and set up labels the way you need them (f).

Microtutorial code at https://rupertoverall.net/Rtrack/microtutorials/plotting.html

rupertoverall.net
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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 13mo ago

@AlSweigart@mastodon.social Can't an LLM also just write a test suite (and explain/comment the code if necessary)?

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Open post
Rupert Overall @rupertoverall@fosstodon.org
· 15mo ago
Replying to
@dcz@fosstodon.org Also true. It has been said that the best person to teach something is someone who just learnt it. I guess authors can get too close to the work that they don't anticipate real-world user problems well.
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