The eyes have it
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A non-profit open-access journal for research in the life and biomedical sciences working to improve research culture and communication.
New findings suggest sideways walking in crabs is a rare but innovative trait originating from a common ancestor, and provide a framework for understanding how animal locomotion diversifies and persists over time.
Geomagnetic and visual cues guide seasonal migratory orientation in the nocturnal fall armyworm, the world’s most invasive insect
https://elifesciences.org/articles/109098?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Auditory perception and neural representation of temporal features are altered by age but not by cochlear synaptopathy
https://elifesciences.org/articles/102890?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Publish in a format that fits 📑
Alongside Research Articles, we also publish scientific discoveries in the form of Tools and Resources papers, Research Advances and Short Reports.
Herbivorous insects independently evolved salivary effectors to regulate plant immunity by destabilizing the malectin-LRR RLP NtRLP4
https://elifesciences.org/articles/108737?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Physiology is full of hidden rules.
We feature studies that reveal these principles through precise experiments and predictive models, showing how cells regulate activity and adapt to change.
Human adherent cortical organoids in a multi-well format
https://elifesciences.org/articles/98340?utm_source=mastodon&utm_medium=social&utm_campaign=organic
We are now accepting submissions in Physiology.
We review quantitative experimental and computational research that uncovers mechanisms driving biological function across levels of organisation, with emphasis on cellular and molecular physiology.
Permissive and instructive Hox codes govern limb positioning
https://elifesciences.org/articles/100592?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Fitness drivers of division of labor in vertebrates
https://elifesciences.org/articles/105501?utm_source=mastodon&utm_medium=social&utm_campaign=organic
"When you publish with eLife, you have full control over how you revise after peer review, giving you more agency over the direction of your work.
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Separating selection from mutation in antibody language models
https://elifesciences.org/articles/109644?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Rethinking how memories are retrieved
https://elifesciences.org/articles/111126?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Dynamic modulation of social gaze by sex and familiarity in marmoset dyads
https://elifesciences.org/articles/105034?utm_source=mastodon&utm_medium=social&utm_campaign=organic
A conserved mycobacterial nucleomodulin hijacks the host COMPASS complex to reprogram pro-inflammatory transcription and promote intracellular survival
https://elifesciences.org/articles/107677?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Human exploration strategically balances approaching and avoiding uncertainty
https://elifesciences.org/articles/94231?utm_source=mastodon&utm_medium=social&utm_campaign=organic
How enzymes make the right choice during biosynthesis
https://elifesciences.org/articles/111042?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Death receptor 6 does not regulate axon degeneration and Schwann cell injury responses during Wallerian degeneration
https://elifesciences.org/articles/108389?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Canonical neurodevelopmental trajectories of structural and functional manifolds
https://elifesciences.org/articles/103097?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Real-time transcriptomic profiling in distinct experimental conditions
https://elifesciences.org/articles/98768?utm_source=mastodon&utm_medium=social&utm_campaign=organic
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Dynamic architecture of mycobacterial outer membranes revealed by all-atom simulations
https://elifesciences.org/articles/108644?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability
https://elifesciences.org/articles/105398?utm_source=mastodon&utm_medium=social&utm_campaign=organic
HER2-driven mammary tumorigenesis enhances bioenergetics despite reductions in mitochondrial content
https://elifesciences.org/articles/104079?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Hugin-AstA circuitry is a novel central energy sensor that directly regulates sweet sensation in Drosophila and mouse
https://elifesciences.org/articles/108551?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Natural xanthones as α-Mangostin induce vasorelaxation involving key gating residues in the S6 domain of BK channels
https://elifesciences.org/articles/109479?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Investments in photoreceptors compete with investments in optics to determine eye design
https://elifesciences.org/articles/96517?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
https://elifesciences.org/articles/106587?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Check out our Digest section, showcasing the latest research with short, easy to read summaries: https://elifesciences.org/digests?utm_source=mastodon&utm_medium=social&utm_campaign=organic
"Find short, easy to read summaries of the latest research with eLife Digest articles 💡
https://elifesciences.org/digests?utm_source=mastodon&utm_medium=social&utm_campaign=organic"
The self-interest of adolescents overrules cooperation in social dilemmas
https://elifesciences.org/articles/106840?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Probing metazoan polyphosphate biology using Drosophila reveals novel and conserved polyP functions
https://elifesciences.org/articles/104841?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Fully computational design of PAM-relaxed Staphylococcus aureus Cas9 with expanded targeting capability using UniDesign
https://elifesciences.org/articles/110906?utm_source=mastodon&utm_medium=social&utm_campaign=organic
DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci
https://elifesciences.org/articles/102489?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Nociceptor neurons control pollution-mediated neutrophilic asthma
https://elifesciences.org/articles/101988?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Cocaine disrupts hidden states in the brain
https://elifesciences.org/articles/111296?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Extracellular vesicle-mediated release of bis(monoacylglycerol)phosphate is regulated by LRRK2 and glucocerebrosidase activity
https://elifesciences.org/articles/106330?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Investigating the native functions of [NiFe]-CODH through genomic context analysis
https://elifesciences.org/articles/108780?utm_source=mastodon&utm_medium=social&utm_campaign=organic
How membranes shape up for lipid transfer
https://elifesciences.org/articles/111373?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Continuous flash suppression of neural responses and population orientation coding in macaque V1
https://elifesciences.org/articles/107518?utm_source=mastodon&utm_medium=social&utm_campaign=organic
We review research in Genetics and Genomics, including the genetic basis of health and disease, epigenetics, genomics, population genetics and more.
Read the latest research ⬇️
A structural code for assembly specificity in GID/CTLH-type E3 ligases
https://elifesciences.org/articles/110152?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Collective epithelial migration mediated by the unbinding of hexatic defects
https://elifesciences.org/articles/105397?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Detecting directed motion and confinement in single-particle trajectories using hidden variables
https://elifesciences.org/articles/99347?utm_source=mastodon&utm_medium=social&utm_campaign=organic
Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons
https://elifesciences.org/articles/104006?utm_source=mastodon&utm_medium=social&utm_campaign=organic