mastodon 4.7.3Das "Deutsche Zentrum für Neurodegenerative Erkrankungen" (DZNE) forscht zu Erkrankungen des Gehirns und Nervensystems, wie z. B. #Alzheimer, #Parkinson und #ALS. Toots in Deutsch und Englisch - D. Bayer (db), M. Neitzert (mn)
New paper out: Drawing a line: Differentiating mild from moderate dementia using the functional activities questionnaire.: Ersözlü, Ersin; Preis, Lukas; Aktuz, Aykut; et al.
The journal of prevention of Alzheimer's disease Vol. 13, no. 8, p. 100630 - http://dlvr.it/TTgVfh | Please share #dzne #papers
New paper out: Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications: Lange, Lara M; Fang, Zih-Hua; Makarious, Mary B; et al.
The lancet Vol. 25, no. 8, p. 741 - 754 http://dlvr.it/TThMxr | Please share #dzne #papers
New paper out: PinkyCaMP: an mScarlet-based calcium sensor with enhanced brightness, photostability and multiplexing capabilities.: Fink, Ryan; Imai, Shosei; Gockel, Nala Eileen; et al.
Nature methods Vol. 23, no. 5, p. 998 - 1010 http://dlvr.it/TSjDQj | Please share #dzne #papers
New paper out: Arbeitsbedingungen von beruflich Pflegenden und deren Folgen, Teil 3: Schmidt, Sascha G.; Dichter, Martin; Hasselhorn, Hans M.
Lebenswelt Heim http://dlvr.it/TShlrx | Please share #dzne #papers
New paper out: New evidence on the clinical, genetic, and biochemical bases of GBA1-Parkinson's disease: prospects for treatment.: Menozzi, Elisa; Toffoli, Marco; Deleidi, Michela; et al.
The lancet Vol. 25, no. 6, p. 602 - 614 http://dlvr.it/TShKP5 | Please share #dzne #papers
New paper out: IgLON5 autoimmune antibodies activate Tau via neuronal hyperactivity.: Askin, Bilge; Kilic, Cagla; Cordero Gómez, César; et al.
Science advances Vol. 12, no. 20, p. eaec2042 http://dlvr.it/TSh9fW | Please share #dzne #papers
New paper out: Minor neuropsychological deficits and stage 2 of Alzheimer's disease.: Stark, Melina; Wagner, Michael; Kuhn, Elizabeth; et al.
Alzheimer's and dementia Vol. 22, no. 5, p. e71458 http://dlvr.it/TSg94Q | Please share #dzne #papers
New paper out: Dataset: A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model. Kreye et al, v1: Kreye, Jakob; Reincke, Momsen; Kornau, Hans-Christian; et al.
http://dlvr.it/TSZhj0 | Please share #dzne #papers
New paper out: Dataset: Early IFN-a signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19, v2: Kraemer, Benjamin; Schultze, Joachim L.; Krämer, Benjamin; et al.
http://dlvr.it/TSZDMX | Please share #dzne #papers
New paper out: Dataset: Discovering unifying disease recovery dynamics in COVID-19. Frishberg et al., v1: Frishberg, Amit; Shen-Orr, Shai; Frishberg, Amit; et al.
http://dlvr.it/TSYCGp | Please share #dzne #papers
New paper out: Dataset: Axon initial segment dynamics during associative fear learning.: Benoit, Chloe; Ganea, Dan Alin; Paricio-Montesinos, Ricardo; et al.
http://dlvr.it/TSRdPk | Please share #dzne #papers
New paper out: Software: Axon initial segment dynamics during associative fear learning, v1: Benoit, Chloe; Ganea, Dan Alin; Paricio-Montesinos, Ricardo; et al.
http://dlvr.it/TSRPds | Please share #dzne #papers
New paper out: Early Alzheimer´s disease blood biomarkers are associated with a higher risk for postoperative long-term cognitive decline: Insights from the FINDERI study.: Hansen, Niels; Sadlonova, Monika; Esselmann, Hermann; et al.
Alzheimer's and dementia Vol. 22, no. 7, p. e71631 http://dlvr.it/TTj5tv | Please share #dzne #papers
New paper out: Dataset: Multi-omic single-nucleus ATAC-seq + RNA-seq of nuclei from the post-mortem human primary motor cortex from patients with ALS, ALS-FTD, C9ORF72-ALS-FTD and neurologically unaffected controls, v1: Grozdanov, Veselin; Danzer, Karin
http://dlvr.it/TSSLr3 | Please share #dzne #papers
New paper out: Dataset: Validity and value of metabolic connectivity in mouse models of β-amyloid and tauopathy, v2: Ruch, Francois; Ruch, Francois
http://dlvr.it/TSYR55 | Please share #dzne #papers
New paper out: Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points.: Grobe-Einsler, Marcus; Maas, Vivian; Amin, Arian Taheri; et al.
Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1370 - 1378 http://dlvr.it/TTfHd8 | Please share #dzne #papers
New paper out: Evidence for early, clinically silent medial temporal lobe inflammation after CAR-T cell therapy.: Dubai, Marwa Al; Rebello, Mahima Verginia; Neumann, Katja; et al.
European journal of cancer Vol. 244, p. 116925 - http://dlvr.it/TTh9Br | Please share #dzne #papers
New paper out: Aquaporin-4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders.: Ranke, Jonas; Steinacker, Petra; Halbgebauer, Steffen; et al.
Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1498 - 1502 http://dlvr.it/TTfNt5 | Please share #dzne #papers
New paper out: 3D print file for a replacement of Tokaihit magnetic lid for chamber slides: Fu, Yangting
http://dlvr.it/TSSCV0 | Please share #dzne #papers
New paper out: Dataset: Supplementary Figures Tabular Data - The mitochondrial unfolded protein response disrupts neuronal–glial communication and promotes senescence in human microglia (v2): Pérez-Jiménez, María José; Bertoli, Federico; Weissleder, Christin; et al.
http://dlvr.it/TSTKSk | Please share #dzne #papers
New paper out: Dataset: Data from: A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology: Dannert, Angelika; Schulz, Nathalie; Klimmt, Julien; et al.
http://dlvr.it/TSXVgR | Please share #dzne #papers
New paper out: Potential proteomic biomarkers for monitoring clinical studies in Duchenne/Becker muscular dystrophy.: Dowling, Paul; Bouragba, Dounia; Negroni, Elisa; et al.
Expert review of proteomics Vol. 23, no. 4-5, p. 109 - 120 http://dlvr.it/TSgP5P | Please share #dzne #papers
New paper out: Prevalence of delirium in German nursing homes: A cross-sectional study.: Houdelet-Oertel, Alexandre; Dörner, Jonas; Walter, Roberto; et al.
BMC geriatrics Vol. 26, no. 1, p. 938 http://dlvr.it/TTgH9N | Please share #dzne #papers
New paper out: Co-regulation of HIV control and cytomegalovirus pp65-specific IL-1β and TNF-α responses by genetic variants in the MHC region.: Ruijten, Suzanne D E; Dos Santos, Jéssica C; Rios-Vazquez, Victoria; et al.
PLoS pathogens Vol. 22, no. 7, p. e1014355 - http://dlvr.it/TThtlk | Please share #dzne #papers
New paper out: Evidence-based care pathways for people with dementia and neurodegenerative disorders in Europe: a systematic review of models, integration of digital technologies, and quality indicators.: Cardona, Maria Isabel; Gakoudis, Parthena Nena; Macijauskienė, Jūratė; et al.
Frontiers in medicine Vol. 13, p. 1774318 http://dlvr.it/TTjSV9 | Please share #dzne #papers
New paper out: Dataset: PNN unit analysis, v1: Dityatev, Alexander; Dityatev, Alexander
http://dlvr.it/TSZMhD | Please share #dzne #papers
New paper out: DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general population.: Liu, Dan; Talevi, Valentina; Tavares, Juliana F; et al.
EBioMedicine Vol. 128, p. 106289 - http://dlvr.it/TShd6T | Please share #dzne #papers
New paper out: Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study: Bouzigues, Arabella; Grassi, Mario; Cantoni, Valentina; et al.
The lancet Vol. 25, no. 8, p. 731 - 740 http://dlvr.it/TTdkMK | Please share #dzne #papers
New paper out: Variational sparse Gaussian-process method for detecting spatially variable genes and cellular interactions in spatial transcriptomics.: Wang, Zhicong; Li, Jing; Xie, Liqing; et al.
Briefings in bioinformatics Vol. 27, no. 4, p. bbag371 http://dlvr.it/TTdVpL | Please share #dzne #papers
New paper out: Dataset: Single-nucleus RNA-seq of human post-mortem primary motor cortex (M1) nuclei from ALS-FTD patients, NeuN+ (neuronal) and sorted for TDP-43 low vs. high signal, v1: Grozdanov, Veselin; Danzer, Karin
http://dlvr.it/TSSxsf | Please share #dzne #papers
New paper out: Dataset: Main Figures Tabular Data - The mitochondrial unfolded protein response disrupts neuronal–glial communication and promotes senescence in human microglia (v3): Pérez-Jiménez, María José; Raji, Hariam; Bertoli, Federico; et al.
http://dlvr.it/TSSgWg | Please share #dzne #papers
New paper out: Neuroimaging Correlates of Post-Stroke Pain After Ischemic Stroke: Secondary Analysis of the INSPiRE-TMS Trial.: Stegemann, Alina; Rios, Ana Sofia; Khalil, Ahmed; et al.
Human brain mapping Vol. 47, no. 10, p. e70602 http://dlvr.it/TTgBGM | Please share #dzne #papers
New paper out: Spatio-temporal gait signatures across prodromal and early Parkinson's disease in two independent cohorts.: Zatti, Cinzia; Hansen, Clint; Rizzardi, Andrea; et al.
Scientific reports Vol. 16, no. 1, p. 21897 http://dlvr.it/TTdPg5 | Please share #dzne #papers
New paper out: The In Vivo Microstructural Profile of Human Hippocampal Subfield CA1 and Its Relation to Memory Performance.: Hayek, Dayana; Höpker-Fernandes, Joseph; Vockert, Niklas; et al.
Human brain mapping Vol. 47, no. 7, p. e70542 http://dlvr.it/TShtQD | Please share #dzne #papers
New paper out: Reply to the Letter to the Editor: Blind spots in radiology leadership regarding human resources and organization management in the era of artificial intelligence.: Wichtmann, Barbara D; Paech, Daniel; Pianykh, Oleg S; et al.
European radiology Vol. 36, no. 8, p. 6842 - 6844 http://dlvr.it/TTcB10 | Please share #dzne #papers
New paper out: HTZ-1/H2A.Z expression sustains transcriptional programs that regulate Caenorhabditis elegans lifespan.: Xie, Beijia; Scifo, Enzo; Menegatou, Ioanna-Maria; et al.
Mechanisms of ageing and development Vol. 232, p. 112217 - http://dlvr.it/TTcYZD | Please share #dzne #papers
New paper out: Dataset: Data and statistical analysis for research article on Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes published in Cells by Arnst et al. (2021), v1: Dityatev, Alexander
http://dlvr.it/TSZ4R2 | Please share #dzne #papers
New paper out: Value of MRI Outcomes for Preventive and Early-Stage Trials in Spinocerebellar Ataxias 1 and 3.: Rezende, Thiago J R; Petit, Emilien; Park, Young Woo; et al.
Annals of Clinical and Translational Neurology Vol. 13, no. 7, p. 1452 - 1466 http://dlvr.it/TTfcfs | Please share #dzne #papers
New paper out: APTw CEST MRI in therapy-naive IDH-wildtype glioblastoma: insights into tumor heterogeneity and molecular subtypes.: Zeyen, Thomas; Decker, Andreas; Krause, Inga; et al.
Journal of neuro-oncology Vol. 178, no. 1, p. 9 http://dlvr.it/TSgclX | Please share #dzne #papers
New paper out: Data from: Microglial motility is modulated by neuronal activity and correlates with dendritic spine plasticity in the hippocampus of awake mice: Nebeling, Felix; Fuhrmann, Martin; Diseases, German Center for Neurodegenerative
http://dlvr.it/TSXkYX | Please share #dzne #papers
New paper out: Phenotypic spectrum of FGF14-related late-onset ataxia: predominant tremor and cognitive decline as key features of SCA27A.: Möller, Meret; Fienemann, André; Trinh, Joanne; et al.
Journal of neurology Vol. 273, no. 6, p. 309 http://dlvr.it/TSh1td | Please share #dzne #papers
New paper out: Miro1 mutations disrupt cellular calcium homeostasis via dysregulation of mitochondria-ER-contact-sites, rendering iPSC-derived neurons more susceptible to lipid peroxidation.: Bartalis, Anna E; Genschmar, Jack; Fitzgerald, Julia C; et al.
Neurobiology of disease Vol. 227, p. 107492 - http://dlvr.it/TTc3Lf | Please share #dzne #papers
New paper out: Habenula volume alterations in adults born very preterm.: Stüwe, Theresa; Maurer, Angelika; Daamen, Marcel; et al.
Scientific reports Vol. 16, no. 1, p. 22071 http://dlvr.it/TThyVx | Please share #dzne #papers
New paper out: Dataset: Supplemental Material, Marchetti Giovanni and Gaia Tavosanis, Manuscript submitted to Current Biology, 2017, v3: Marchetti, Giovanni; Tavosanis, Gaia
http://dlvr.it/TSXH3b | Please share #dzne #papers
New paper out: Benutzerhandbuch für die deutschsprachige QUALIDEM Version 2.0: Dichter, Martin; Ettema, Teake P.; Schwab, Christian; et al.
http://dlvr.it/TSqjTG | Please share #dzne #papers
New paper out: Synaptophysin density underestimates synapse counts in the human brain - An anatomical study on synaptoporin protein expression.: Woelfle, Sarah; Schön, Michael; Pedro, Maria T; et al.
Neurobiology of disease Vol. 227, p. 107503 - http://dlvr.it/TTbzk7 | Please share #dzne #papers
New paper out: Anti-NMDAR encephalitis impairs intrinsic hippocampal dynamics through neuronal hypercoupling, hub dominance, and aberrant ensembles.: Rahmati, Vahid; Graf, Jürgen; Ceanga, Mihai; et al.
Molecular psychiatry Vol. 31, no. 8, p. 4550 - 4562 http://dlvr.it/TTh47f | Please share #dzne #papers
New paper out: Dataset: Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells. Reincke et al, v1: Reincke, Momsen; Von Wardenburg, Niels; Homeyer, Marie; et al.
http://dlvr.it/TSYfWd | Please share #dzne #papers
New paper out: Software: BART: Toolbox for Computational Magnetic Resonance Imaging, v1.0.00: Blumenthal, Moritz; Schaten, Philip; Mackner, Daniel; et al.
http://dlvr.it/TSS3N6 | Please share #dzne #papers
New paper out: Dataset: RNA Selectively Modulates Activity of Virulent Amyloid PSMα3 and Host Defense LL-37 via Phase Separation and Aggregation Dynamics, v3: Rayan, Bader; Barnea, Eilon; Indig, Rinat; et al.
http://dlvr.it/TSSpsr | Please share #dzne #papers